Search results for " Tumors biomarkers"

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Exosomal Hsp60: A Tumor Biomarker?

2019

Exosomes (EXs) are extracellular vesicles containing proteins, DNA, mRNA, non-coding RNAs, such as miRNAs, and lipid. The EXs can be easily isolated from different biological fluids and their content is considered a potential biomarker in various diseases, such as cancer. EXs play an important role in intercellular communication, permitting cells to exchange proteins, lipids, and genetic material in normal and pathological conditions. New data have shown that tumor cells-derived EXs contribute to cancer progression through the modulation of tumor microenvironment. Heat shock proteins 60 kDa (Hsp60) is classically considered mitochondrial proteins with different biological roles. In recent y…

Tumor microenvironmentSettore BIO/16 - Anatomia UmanaExosomes heat shock protein HSP60 Tumors biomarkersCancerBiologymedicine.diseaseMicrovesiclesCell biologyBiomarkerImmune systemHeat shock proteinmicroRNAmedicineHSP60

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